Varaico: Literature-Extracted Genetic Variants

Gene:AKT1
Variant:p.F55Y
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AKT1

NM_001382430.1:p.F55Y

Associated Papers

Genomic Characterization of Preclinical Prostate Cancer Cell Line Models.

Beatson EL et al.

International Journal of Molecular Sciences, 2024

AKT mutant allele-specific activation dictates pharmacologic sensitivities.

Shrestha Bhattarai T et al.

Nature Communications, 2022

Characterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing.

Lang GT et al.

Nature Communications, 2020

33173047 (PubMed )
Supplement: 41467_2020_19342_MOESM7_ESM.xlsx › PGI_fudan_NC_clnical.oc

AKT1 internal tandem duplications and point mutations are the genetic hallmarks of sclerosing pneumocytoma.

Yeh YC et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2020

Phosphorylation sites in the Hook domain of CaVβ subunits differentially modulate CaV1.2 channel function.

Brunet S et al.

Journal of Molecular and Cellular Cardiology, 2015

Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers.

Parikh C et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."