Associated Papers
The structural heterogeneity of AKT autoinhibition.
Xu L et al.
Protein Science : a Publication of the Protein Society, 2026
Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers.
Nussinov R et al.
Plos Computational Biology, 2019
Genomic alterations at the basis of treatment resistance in metastatic breast cancer: clinical applications.
Toss A et al.
Oncotarget, 2018
AKT in cancer: new molecular insights and advances in drug development.
Mundi PS et al.
British Journal of Clinical Pharmacology, 2016
Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine.
Yi KH et al.
Oncotarget, 2013
Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers.
Parikh C et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012
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