Varaico: Literature-Extracted Genetic Variants

Gene:AKT1
Variant:p.D32Y
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AKT1

NM_001382430.1:p.D32Y

Associated Papers

The structural heterogeneity of AKT autoinhibition.

Xu L et al.

Protein Science : a Publication of the Protein Society, 2026

Clinicopathological and molecular characteristics of patients with hypermutant lung cancer: A retrospective cohort study.

Zhang H et al.

Oncology Letters, 2021

33692861 (PubMed )
Supplement: Supplementary_Data.pdf

Early-stage endometrial cancer, CTNNB1 mutations, and the relation between lymphovascular space invasion and recurrence.

Imboden S et al.

Acta Obstetricia Et Gynecologica Scandinavica, 2020

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer.

Thirumal Kumar D et al.

Computers in Biology and Medicine, 2019

Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making.

Abida W et al.

Jco Precision Oncology, 2017

AKT in cancer: new molecular insights and advances in drug development.

Mundi PS et al.

British Journal of Clinical Pharmacology, 2016

Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine.

Yi KH et al.

Oncotarget, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."