Varaico: Literature-Extracted Genetic Variants

Gene:AKT1S1
Variant:p.T246A
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AKT1S1

NM_001098633.4:p.T246A

Associated Papers

Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle.

Wiza C et al.

Archives of Physiology and Biochemistry, 2014

Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.

Wang L et al.

The Journal of Biological Chemistry, 2008

PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.

Wang L et al.

The Journal of Biological Chemistry, 2007

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.

Vander Haar E et al.

Nature Cell Biology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."