Associated Papers
Inhibitors of Transthyretin Amyloidosis: How to Rank Drug Candidates Using X-ray Crystallography Data.
Leite JP et al.
Molecules (basel, Switzerland), 2024
Transthyretin Anti-Amyloidogenic and Fibril Disrupting Activities of Bacopa monnieri (L.) Wettst (Brahmi) Extract.
Eze FN et al.
Biomolecules, 2019
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
Giadone RM et al.
Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis, 2018
Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Alhamadsheh MM et al.
Science Translational Medicine, 2011
Unfolding and aggregation of transthyretin by the truncation of 50 N-terminal amino acids.
Mizuguchi M et al.
Proteins, 2008
Kinetics of inhibition of beta-amyloid aggregation by transthyretin.
Liu L et al.
Biochemistry, 2006
Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation.
Johnson SM et al.
Journal of Medicinal Chemistry, 2005
Dimeric transthyretin variant assembles into spherical neurotoxins.
Matsubara K et al.
Biochemistry, 2005
Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis.
Adamski-Werner SL et al.
Journal of Medicinal Chemistry, 2004
Biophysical analyses of the transthyretin variants, Tyr114His and Tyr116Ser, associated with familial amyloidotic polyneuropathy.
Shinohara Y et al.
Biochemistry, 2003
Search for intermediate structures in transthyretin fibrillogenesis: soluble tetrameric Tyr78Phe TTR expresses a specific epitope present only in amyloid fibrils.
Redondo C et al.
Journal of Molecular Biology, 2000
The molecular interaction of 4'-iodo-4'-deoxydoxorubicin with Leu-55Pro transthyretin 'amyloid-like' oligomer leading to disaggregation.
Sebastião MP et al.
The Biochemical Journal, 2000
4'-Iodo-4'-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid.
Palha JA et al.
The American Journal of Pathology, 2000
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