Varaico: Literature-Extracted Genetic Variants

Gene:ALK
Variant:p.R1275G
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ALK

NM_004304.5:p.R1275G

Associated Papers

A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers.

Guerra AD et al.

Nature Communications, 2025

40813394 (PubMed )
Supplement: 41467_2025_62979_MOESM4_ESM.xlsx › Figure_2B

Germline ALK variations are associated with a poor prognosis in glioma and IDH-wildtype glioblastoma.

Bu L et al.

Journal of Neuro-oncology, 2021

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