Varaico: Literature-Extracted Genetic Variants

Gene:ALK
Variant:p.L1240V
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ALK

NM_004304.5:p.L1240V

Associated Papers

Genomic ALK alterations in primary and relapsed neuroblastoma.

Rosswog C et al.

British Journal of Cancer, 2023

36807339 (PubMed )
Supplement: 41416_2023_2208_MOESM1_ESM.pdf

Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing.

Szymansky A et al.

Journal of Personalized Medicine, 2021

34442335 (PubMed )
Supplement: jpm-11-00691-s001.zip › S11-SNVs_reference_cohort.xlsx › Tabelle1

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Low Frequency ALK Hotspots Mutations In Neuroblastoma Tumours Detected By Ultra-deep Sequencing: Implications For ALK Inhibitor Treatment.

Javanmardi N et al.

Scientific Reports, 2019

Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma.

Braekeveldt N et al.

Cancer Research, 2018

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.

Ma X et al.

Nature, 2018

29489755 (PubMed )
Supplement: NIHMS939556-supplement-Table_2-7.xlsx › TableS5

Anaplastic Lymphoma Kinase as a Cancer Target in Pediatric Malignancies.

Mossé YP

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment.

Lambertz I et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma.

Bresler SC et al.

Cancer Cell, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."