Varaico: Literature-Extracted Genetic Variants

Gene:ALK
Variant:p.G1201E
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ALK

NM_004304.5:p.G1201E

Associated Papers

ALK Inhibition Prolongs Survival in a Mouse Model of ALK-Positive Anaplastic Thyroid Cancer.

Machlah YM et al.

Thyroid : Official Journal of the American Thyroid Association, 2025

Mutational profiling using liquid biopsy to guide targeted therapy in patients with metastatic cancer.

Mazouji O et al.

Scientific Reports, 2025

40169620 (PubMed )
Supplement: 41598_2025_88094_MOESM2_ESM.xlsx › Feuil1

Novel ALK gene mutation in inflammatory myofibroblastic tumor of the thyroid: a case report.

Guangxu Y et al.

Frontiers in Oncology, 2025

The genomic landscape of papillary thyroid carcinoma on next-generation sequencing in patients undergoing total thyroidectomy.

Poongkodi K et al.

World Journal of Surgery, 2024

Pathway-based, reaction-specific annotation of disease variants for elucidation of molecular phenotypes.

Orlic-Milacic M et al.

Database : the Journal of Biological Databases and Curation, 2024

38713862 (PubMed )
Supplement: baae031_supp.zip › suppl_data › Database_Orlic_Milacic_Reactome_of_Disease_Variants_SupplementaryTable1.docx

Multifaceted Roles of ALK Family Receptors and Augmentor Ligands in Health and Disease: A Comprehensive Review.

Katic L et al.

Biomolecules, 2023

First-line crizotinib therapy is effective for a novel SEC31A-anaplastic lymphoma kinase fusion in a patient with stage IV lung adenocarcinoma: a case report and literature reviews.

Wu R et al.

Anti-cancer Drugs, 2023

Molecular diagnosis and targeted treatment of advanced follicular cell-derived thyroid cancer in the precision medicine era.

Capdevila J et al.

Cancer Treatment Reviews, 2022

Anaplastic lymphoma kinase-special immunity and immunotherapy.

Guo Y et al.

Frontiers in Immunology, 2022

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Oncogenic ALK F1174L drives tumorigenesis in cutaneous squamous cell carcinoma.

Gualandi M et al.

Life Science Alliance, 2020

Development and Analytical Validation of an Expanded Mutation Detection Panel for Next-Generation Sequencing of Thyroid Nodule Aspirates.

Ablordeppey KK et al.

The Journal of Molecular Diagnostics : Jmd, 2020

Molecular Alterations in Thyroid Cancer: From Bench to Clinical Practice.

Tirrò E et al.

Genes, 2019

Unique mutation patterns in anaplastic thyroid cancer identified by comprehensive genomic profiling.

Khan SA et al.

Head & Neck, 2019

Targeting anaplastic lymphoma kinase in neuroblastoma.

Umapathy G et al.

Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2019

Anaplastic lymphoma kinase L1198F and G1201E mutations identified in anaplastic thyroid cancer patients are not ligand-independent.

Guan J et al.

Oncotarget, 2017

Personalized therapy in patients with anaplastic thyroid cancer: targeting genetic and epigenetic alterations.

Smith N et al.

The Journal of Clinical Endocrinology and Metabolism, 2015

ALK-rearrangements and testing methods in non-small cell lung cancer: a review.

Shackelford RE et al.

Genes & Cancer, 2014

Recent progress of genome study for anaplastic thyroid cancer.

Lee J et al.

Genomics & Informatics, 2013

Identification of ALK germline mutation (3605delG) in pediatric anaplastic medulloblastoma.

Coco S et al.

Journal of Human Genetics, 2012

Diagnostic and prognostic markers in differentiated thyroid cancer.

Gómez Sáez JM

Current Genomics, 2011

Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene.

Murugan AK et al.

Cancer Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."