Varaico: Literature-Extracted Genetic Variants

Gene:ALK
Variant:p.R1181H
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ALK

NM_004304.5:p.R1181H

Associated Papers

Age-Related Multigene Analysis of Colorectal Cancer Using Next-Generation Sequencing.

Kozlowska-Geller M et al.

Cancers, 2025

Multiplexed in vivo base editing identifies functional gene-variant-context interactions.

Acosta J et al.

Biorxiv : the Preprint Server for Biology, 2025

40060482 (PubMed )
Supplement: media-4.xlsx › Table_S2A

Molecular tumor board: molecularly adjusted therapy upon identification and functional validation of a novel ALK resistance mutation in a case of lung adenocarcinoma.

Arndt A et al.

The Oncologist, 2025

An in silico evaluation of lorlatinib as a potential therapy for novel amino acid substitutions in the tyrosine kinase domain of the ALK protein associated with cancer.

Zapata Dongo RJ et al.

Frontiers in Pharmacology, 2025

A novel alectinib-sensitive CTNND1-ALK fusion in a lung adenocarcinoma patient: a case report.

Tian X et al.

Investigational New Drugs, 2022

Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients.

Yang J et al.

Frontiers in Oncology, 2021

33898318 (PubMed )
Supplement: Table_1.xlsx › Sheet1

Applied precision medicine in metastatic pancreatic ductal adenocarcinoma.

Taghizadeh H et al.

Therapeutic Advances in Medical Oncology, 2020

Heterogeneous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing.

Guo Q et al.

Molecular Cancer, 2018

30153823 (PubMed )
Supplement: 12943_2018_875_MOESM3_ESM.xlsx › Table_S2_ctDNA_Alterations
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."