Varaico: Literature-Extracted Genetic Variants

Gene:ALK
Variant:p.I1171M
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ALK

NM_004304.5:p.I1171M

Associated Papers

A comprehensive functional atlas of ALK kinase domain variants reveals resistance landscape to ALK inhibitors.

Oh HC et al.

Genome Biology, 2026

ALKTERNATE: A Pilot Study Alternating Lorlatinib With Crizotinib in ALK-Positive NSCLC With Prior ALK Inhibitor Resistance.

Itchins M et al.

Jto Clinical and Research Reports, 2024

Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.

Shiba-Ishii A et al.

Nature Cancer, 2022

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