Varaico: Literature-Extracted Genetic Variants

Gene:ALK
Variant:p.L1152V
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ALK

NM_004304.5:p.L1152V

Associated Papers

HIP1-ALK-Rearranged Lung Cancer in a Young Adult With BRAF V600E Mutation Detected After ALK Tyrosine Kinase Inhibitor Therapy: A Case Report.

Ogimoto A et al.

Jto Clinical and Research Reports, 2024

Clinicopathological features and resistance mechanisms in HIP1-ALK-rearranged lung cancer: A multicenter study.

Kang J et al.

Genes, Chromosomes & Cancer, 2022

Association of anaplastic lymphoma kinase variants and alterations with ensartinib response duration in non-small cell lung cancer.

Hou D et al.

Thoracic Cancer, 2021

34288491 (PubMed )
Supplement: TCA-12-2388-s001.docx

Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer.

Horn L et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2019

Insight into drug resistance mechanisms and discovery of potential inhibitors against wild-type and L1196M mutant ALK from FDA-approved drugs.

Li J et al.

Journal of Molecular Modeling, 2016

Resistance mechanisms after tyrosine kinase inhibitors afatinib and crizotinib in non-small cell lung cancer, a review of the literature.

van der Wekken AJ et al.

Critical Reviews in Oncology/hematology, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."