Varaico: Literature-Extracted Genetic Variants

Gene:ALK
Variant:p.R1120W
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ALK

NM_004304.5:p.R1120W

Associated Papers

An in silico evaluation of lorlatinib as a potential therapy for novel amino acid substitutions in the tyrosine kinase domain of the ALK protein associated with cancer.

Zapata Dongo RJ et al.

Frontiers in Pharmacology, 2025

Longitudinal monitoring by next-generation sequencing of plasma cell-free DNA in ALK rearranged NSCLC patients treated with ALK tyrosine kinase inhibitors.

Kwon M et al.

Cancer Medicine, 2022

35437925 (PubMed )
Supplement: CAM4-11-2944-s002.xlsx › Sheet1

Usefulness of Circulating Tumor DNA in Identifying Somatic Mutations and Tracking Tumor Evolution in Patients With Non-small Cell Lung Cancer.

Roosan MR et al.

Chest, 2021

33878340 (PubMed )
Supplement: mmc1.pdf

Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial.

Bertucci F et al.

Genome Medicine, 2021

34006291 (PubMed )
Supplement: 13073_2021_897_MOESM3_ESM.xlsx › Table_S2

Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non-Small Cell Lung Cancer.

Aggarwal C et al.

Jama Oncology, 2019

Down's Syndrome and Triple Negative Breast Cancer: A Rare Occurrence of Distinctive Clinical Relationship.

Dey N et al.

International Journal of Molecular Sciences, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."