Varaico: Literature-Extracted Genetic Variants

Gene:ALKBH3
Variant:p.D193A
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ALKBH3

NM_139178.4:p.D193A

Associated Papers

Identification of ALKBH6 as a nucleotide demethylase with a distinct substrate preference.

Das S et al.

The Journal of Biological Chemistry, 2025

Feedback regulation between histone lactylation and ALKBH3-mediated glycolysis regulates age-related macular degeneration pathology.

Wang Y et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis.

Kuang W et al.

Cell Discovery, 2022

Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase.

Mohan M et al.

Nucleic Acids Research, 2019

The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA.

Dominissini D et al.

Nature, 2016

Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.

Sundheim O et al.

The Embo Journal, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."