Varaico: Literature-Extracted Genetic Variants

Gene:ALOX5
Variant:p.E254K
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ALOX5

NM_000698.5:p.E254K

Associated Papers

Insights into human history and complex traits from the genomes of African populations.

Bitsue HK et al.

Molecular Biology and Evolution, 2026

Association between a single nucleotide polymorphism of the ALOX5 gene and susceptibility to multisystem tuberculosis in a Chinese Han population.

Zhang J et al.

Microbial Pathogenesis, 2023

Genetic Analysis of TB Susceptibility Variants in Ghana Reveals Candidate Protective Loci in SORBS2 and SCL11A1 Genes.

Asante-Poku A et al.

Frontiers in Genetics, 2021

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM11_ESM.xlsx › SD7_-_Drug_Targets

Targeted deep resequencing of ALOX5 and ALOX5AP in patients with diabetes and association of rare variants with leukotriene pathways.

Postula M et al.

Experimental and Therapeutic Medicine, 2016

The role of lipoxygenases in pathophysiology; new insights and future perspectives.

Mashima R et al.

Redox Biology, 2015

ALOX5 is associated with tuberculosis in a subset of the pediatric population of North China.

Shen C et al.

Genetic Testing and Molecular Biomarkers, 2013

Functional characterization of genetic enzyme variations in human lipoxygenases.

Horn T et al.

Redox Biology, 2013

Association of 5-lipoxygenase gene polymorphisms with bronchial asthma.

Bai C et al.

Experimental and Therapeutic Medicine, 2012

DNA sequence variation and regulation of genes involved in pathogenesis of pulmonary tuberculosis.

Qidwai T et al.

Scandinavian Journal of Immunology, 2012

Association of the -1072G/A polymorphism in the LTC4S gene with asthma in an Indian population.

Kumar A et al.

International Archives of Allergy and Immunology, 2012

Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.

Yoshida T et al.

International Journal of Molecular Medicine, 2009

Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

Küry S et al.

Bmc Cancer, 2008

5-lipoxygenase and 5-lipoxygenase-activating protein gene polymorphisms, dietary linoleic acid, and risk for breast cancer.

Wang J et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2008

Association studies of ALOX5 and bone mineral density in healthy adults.

Foroud T et al.

Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the Usa, 2008

ALOX5 variants associated with susceptibility to human pulmonary tuberculosis.

Herb F et al.

Human Molecular Genetics, 2008

A novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma.

Bai C et al.

International Journal of Molecular Medicine, 2008

Assessment of genetic factors for type 2 diabetes mellitus.

Yamada Y et al.

International Journal of Molecular Medicine, 2006

Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps.

Poole EM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006

Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk.

Goodman JE et al.

Carcinogenesis, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."