Associated Papers
Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial.
Rosenson RS et al.
Nature Medicine, 2023
36879129 (PubMed )
Supplement: 41591_2023_2222_MOESM1_ESM.pdf
Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4.
Landfors F et al.
Journal of Lipid Research, 2023
Genetic and Metabolic Determinants of Plasma Levels of ANGPTL8.
Oldoni F et al.
The Journal of Clinical Endocrinology and Metabolism, 2021
Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia.
Tarugi P et al.
Journal of Biomedical Research, 2019
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
Klarin D et al.
Nature Genetics, 2018
Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus.
Cannon ME et al.
G3 (bethesda, Md.), 2017
Patients with genetically heterogeneous synchronous colorectal cancer carry rare damaging germline mutations in immune-related genes.
Cereda M et al.
Nature Communications, 2016
27377421 (PubMed )
Supplement: ncomms12072-s6.xlsx › Supplementary_Data_5
A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans.
Clapham KR et al.
Bmc Endocrine Disorders, 2016
Insights into blood lipids from rare variant discovery.
Schmidt EM et al.
Current Opinion in Genetics & Development, 2015
Rare and low-frequency variants in human common diseases and other complex traits.
Lettre G
Journal of Medical Genetics, 2014
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
Peloso GM et al.
American Journal of Human Genetics, 2014
High frequency of type 2 diabetes and impaired glucose tolerance in Japanese subjects with the angiopoietin-like protein 8 R59W variant.
Liu J et al.
Journal of Clinical Lipidology, 0
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