Varaico: Literature-Extracted Genetic Variants

Gene:ANK3
Variant:p.W1989R
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ANK3

NM_020987.5:p.W1989R

Associated Papers

Lithium restores inhibitory function and neuronal excitability through GSK-3β inhibition in a bipolar disorder-associated Ank3 variant mouse model.

Caballero-Florán RN et al.

Neuropharmacology, 2025

Lithium Restores Inhibitory Function and Neuronal Excitability through GSK-3β Inhibition in a Bipolar Disorder-Associated Ank3 Variant Mouse Model.

Caballero-Florán RN et al.

Biorxiv : the Preprint Server for Biology, 2025

Ankyrin-G and Its Binding Partners in Neurons: Orchestrating the Molecular Structure of the Axon Initial Segment.

Zhu X et al.

Biomolecules, 2025

Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3β and cyclic AMP signaling pathways.

Piguel NH et al.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2023

Homozygous Missense Variant in the N-Terminal Region of ANK3 Gene Is Associated with Developmental Delay, Seizures, Speech Abnormality, and Aggressive Behavior.

Younus M et al.

Molecular Syndromology, 2023

Roles and mechanisms of ankyrin-G in neuropsychiatric disorders.

Yoon S et al.

Experimental & Molecular Medicine, 2022

Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP.

Nelson AD et al.

Molecular Psychiatry, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."