Varaico: Literature-Extracted Genetic Variants

Gene:ANKK1
Variant:p.A239T
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ANKK1

NM_178510.2:p.A239T

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

ANKK1 Is a Wnt/PCP Scaffold Protein for Neural F-ACTIN Assembly.

Domínguez-Berzosa L et al.

International Journal of Molecular Sciences, 2024

39409035 (PubMed )
Supplement: ijms-25-10705-s001.zip › ijms-3209969-supplementary.pdf

Genomic characteristics and immune landscape of super multiple primary lung cancer.

Yang Z et al.

Ebiomedicine, 2024

38364701 (PubMed )
Supplement: mmc2.xlsx › all_212.somatic.igv_recheck.mut

Decoding the genetic relationship between Alzheimer's disease and type 2 diabetes: potential risk variants and future direction for North Africa.

Boukhalfa W et al.

Frontiers in Aging Neuroscience, 2023

37342358 (PubMed )
Supplement: Table_2.XLSX › Table_2_SNPnexus_annotation

Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.

Cukier HN et al.

Npj Parkinson's Disease, 2022

35768426 (PubMed )
Supplement: 41531_2022_346_MOESM2_ESM.xlsx › SupTab1

Motivational learning biases are differentially modulated by genetic determinants of striatal and prefrontal dopamine function.

Richter A et al.

Journal of Neural Transmission (vienna, Austria : 1996), 2021

34302222 (PubMed )
Supplement: 702_2021_2382_MOESM1_ESM.docx

Analysis of genomic pathogenesis according to the revised Bethesda guidelines and additional criteria.

Kim JC et al.

Journal of Cancer Research and Clinical Oncology, 2021

Association of ANKK1 polymorphism with antipsychotic-induced hyperprolactinemia.

Fedorenko OY et al.

Human Psychopharmacology, 2020

Ankyrin Repeat and Kinase Domain Containing 1 Gene, and Addiction Vulnerability.

Koeneke A et al.

International Journal of Molecular Sciences, 2020

A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response.

Macare C et al.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, 2018

Novel human genome variants associated with alcohol use disorders identified in a Lithuanian cohort.

Baronas K et al.

Acta Medica Lituanic, 2018

Overlapping dopaminergic pathway genetic susceptibility to heroin and cocaine addictions in African Americans.

Levran O et al.

Annals of Human Genetics, 2015

Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions.

Ma Y et al.

Molecular Neurobiology, 2015

Novel gene identified in an exome-wide association study of tanning dependence.

Cartmel B et al.

Experimental Dermatology, 2014

Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction.

Levran O et al.

Pharmacogenomics, 2013

Motivational salience and genetic variability of dopamine D2 receptor expression interact in the modulation of interference processing.

Richter A et al.

Frontiers in Human Neuroscience, 2013

Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood.

Nemoda Z et al.

Neuroscience and Biobehavioral Reviews, 2011

The ANKK1 protein associated with addictions has nuclear and cytoplasmic localization and shows a differential response of Ala239Thr to apomorphine.

Garrido E et al.

Neurotoxicity Research, 2011

Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.

Gelernter J et al.

Human Molecular Genetics, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."