Associated Papers
The Han:SPRD Rat: A Preclinical Model of Polycystic Kidney Disease.
Kofotolios I et al.
Biomedicines, 2024
Experimental Models of Polycystic Kidney Disease: Applications and Therapeutic Testing.
Sieben CJ et al.
Kidney360, 2023
Loss of Anks6 leads to YAP deficiency and liver abnormalities.
Airik M et al.
Human Molecular Genetics, 2020
Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases.
Rothé B et al.
Cellular Signalling, 2020
Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment.
Ashraf S et al.
Nature Communications, 2018
Influence of the R823W mutation on the interaction of the ANKS6-ANKS3: insights from molecular dynamics simulation and free energy analysis.
Kan W et al.
Journal of Biomolecular Structure & Dynamics, 2016
The SAM domain of ANKS6 has different interacting partners and mutations can induce different cystic phenotypes.
Bakey Z et al.
Kidney International, 2015
Anks3 interacts with nephronophthisis proteins and is required for normal renal development.
Yakulov TA et al.
Kidney International, 2015
ANKS3 Co-Localises with ANKS6 in Mouse Renal Cilia and Is Associated with Vasopressin Signaling and Apoptosis In Vivo in Mice.
Delestré L et al.
Plos One, 2015
Mutations in ANKS6 cause a nephronophthisis-like phenotype with ESRD.
Taskiran EZ et al.
Journal of the American Society of Nephrology : Jasn, 2014
Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.
Leettola CN et al.
Bmc Structural Biology, 2014
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Hoff S et al.
Nature Genetics, 2013
Animal models for human polycystic kidney disease.
Nagao S et al.
Experimental Animals, 2012
Polycystic kidney disease in Han:SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.
Nagao S et al.
American Journal of Physiology. Renal Physiology, 2010
The polycystic kidney disease-related proteins Bicc1 and SamCystin interact.
Stagner EE et al.
Biochemical and Biophysical Research Communications, 2009
Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.
Brown JH et al.
Journal of the American Society of Nephrology : Jasn, 2005