Associated Papers
The rs35217482 (T755I) single-nucleotide polymorphism in aldehyde oxidase-1 attenuates prot ein dimer formation and reduces the rates of phthalazine metabolism.
Ueda H et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2022
Genetic variants of aldehyde oxidase (AOX) 1 in cynomolgus and rhesus macaques.
Uno Y et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
Targeted next generation sequencing as a tool for precision medicine.
Gulilat M et al.
Bmc Medical Genomics, 2019
The genetics of gout: towards personalised medicine?
Dalbeth N et al.
Bmc Medicine, 2017
Genomic sequencing of uric acid metabolizing and clearing genes in relationship to xanthine oxidase inhibitor dose.
Carroll MB et al.
Rheumatology International, 2017
Genes implicated in thiopurine-induced toxicity: Comparing TPMT enzyme activity with clinical phenotype and exome data in a paediatric IBD cohort.
Coelho T et al.
Scientific Reports, 2016
Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease.
Moon W et al.
Alimentary Pharmacology & Therapeutics, 2016
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
Ramírez J et al.
Pharmacogenetics and Genomics, 2014
Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine.
Kurzawski M et al.
Therapeutic Drug Monitoring, 2012
The impact of single nucleotide polymorphisms on human aldehyde oxidase.
Hartmann T et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2012
Inosine triphosphate pyrophosphatase 94C>A polymorphism: clinical implications for patients with systemic lupus erythematosus treated with azathioprine.
Yamamoto K et al.
Expert Opinion on Drug Safety, 2010
Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease.
Smith MA et al.
Alimentary Pharmacology & Therapeutics, 2009