Varaico: Literature-Extracted Genetic Variants

Gene:APC
Variant:p.A59T
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APC

NM_000038.6:p.A59T

Associated Papers

Large-scale application of ClinGen-InSiGHT APC-specific ACMG/AMP variant classification criteria leads to substantial reduction in VUS.

Yin X et al.

American Journal of Human Genetics, 2024

39357517 (PubMed )
Supplement: mmc2.xlsx › c_Pred-data

Polyclonality overcomes fitness barriers in Apc-driven tumorigenesis.

Sadien ID et al.

Nature, 2024

39478206 (PubMed )
Supplement: 41586_2024_8053_MOESM5_ESM.xlsx › Fig._2k

Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.

Deycmar S et al.

Journal of Translational Medicine, 2024

Japanese Society of Medical Oncology clinical guidelines: Molecular testing for colorectal cancer treatment, 5th edition.

Bando H et al.

Cancer Science, 2024

38263580 (PubMed )
Supplement: CAS-115-1014-s001.docx

Completion of Genetic Testing and Incidence of Pathogenic Germline Mutation among Patients with Early-Onset Colorectal Cancer: A Single Institution Analysis.

Storandt MH et al.

Cancers, 2023

37509234 (PubMed )
Supplement: cancers-15-03570-s001.zip › cancers-2473295-supplementary.pdf

MN1 altered astroblastoma with APC and LRP1B gene mutations: a unique variant in the cervical spine of a pediatric patient.

Mugge L et al.

Child's Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery, 2023

Mutational Profile and Clonal Evolution of Relapsed/Refractory Diffuse Large B-Cell Lymphoma.

Lee B et al.

Frontiers in Oncology, 2021

33777778 (PubMed )
Supplement: DataSheet_1.xlsx › Supplementary_Data_Set_1

Variations of the UNC13D gene in patients with autoimmune lymphoproliferative syndrome.

Aricò M et al.

Plos One, 2013

Comprehensive mutation analysis in colorectal flat adenomas.

Voorham QJ et al.

Plos One, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."