Varaico: Literature-Extracted Genetic Variants

Gene:APC
Variant:p.P301S
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APC

NM_000038.6:p.P301S

Associated Papers

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.

Litvinchuk A et al.

Neuron, 2024

APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.

Chen Y et al.

Cell, 2024

Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.

Shi Y et al.

Neuron, 2021

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.

Wang C et al.

Neuron, 2021

Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation.

Ossola B et al.

Glia, 2016

Mutational spectrum of the APC and MUTYH genes and genotype-phenotype correlations in Brazilian FAP, AFAP, and MAP patients.

Torrezan GT et al.

Orphanet Journal of Rare Diseases, 2013

Tau, where are we now?

Johnson GV et al.

Journal of Alzheimer's Disease : Jad, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."