Varaico: Literature-Extracted Genetic Variants

Gene:APC
Variant:p.L360*
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APC

NM_000038.6:p.L360*

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10

Therapeutic Potential of Translational Readthrough at Disease-Associated Premature Termination Codons From Tumor Suppressor Genes.

Torices L et al.

Iubmb Life, 2025

Novel read through agent: ZKN-0013 demonstrates efficacy in APCmin model of familial adenomatous polyposis.

Graf MR et al.

Journal of Molecular Medicine (berlin, Germany), 2023

Mutation Spectrum of Familial Adenomatous Polyposis Patients in Turkish Population: Identification of 3 Novel APC Mutations.

Arslan Ateş E et al.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology, 2022

Adenomatous polyposis coli in cancer and therapeutic implications.

Noe O et al.

Oncology Reviews, 2021

Characterization of new-generation aminoglycoside promoting premature termination codon readthrough in cancer cells.

Bidou L et al.

Rna Biology, 2017

A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents.

Caspi M et al.

Journal of Molecular Medicine (berlin, Germany), 2016

Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cells.

Floquet C et al.

Plos One, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."