Associated Papers
Decay of driver mutations shapes the landscape of intestinal transformation.
Lourenço FC et al.
Nature, 2026
Building a hereditary cancer program in Colombia: analysis of germline pathogenic and likely pathogenic variants spectrum in a high-risk cohort.
Sanabria-Salas MC et al.
European Journal of Human Genetics : Ejhg, 2025
Multiplexed in vivo base editing identifies functional gene-variant-context interactions.
Acosta J et al.
Biorxiv : the Preprint Server for Biology, 2025
Clinical Validation of Local Versus Commercial Genomic Testing in Cancer: A Comparison of Tissue and Plasma Concordance.
Faulkner LG et al.
Cancer Investigation, 2025
Polyclonality overcomes fitness barriers in Apc-driven tumorigenesis.
Sadien ID et al.
Nature, 2024
Engineering of a high-fidelity Cas12a nuclease variant capable of allele-specific editing.
Wei J et al.
Plos Biology, 2024
Genomic profiling and clinical utility of circulating tumor DNA in metastatic prostate cancer: SCRUM-Japan MONSTAR SCREEN project.
Shiota M et al.
Bjc Reports, 2024
Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.
Montes-Rodríguez IM et al.
Cancer Medicine, 2023
Newly discovered genomic mutation patterns in radiation-induced small intestinal tumors of ApcMin/+ mice.
Iizuka D et al.
Plos One, 2023
Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer.
Yu H et al.
Frontiers in Oncology, 2022
Dysregulated immunity in PID patients with low GARP expression on Tregs due to mutations in LRRC32.
Lehmkuhl P et al.
Cellular & Molecular Immunology, 2021
Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.
Cobain EF et al.
Jama Oncology, 2021
Frequency of genomic secondary findings among 21,915 eMERGE network participants.
Unknown Author
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2020
Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis.
Hirsch D et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018
Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia.
Ashktorab H et al.
Oncotarget, 2017
Multiple desmoid tumors in a patient with familial adenomatous polyposis caused by the novel W421X mutation.
Ioannidis O et al.
Revista Espanola De Enfermedades Digestivas, 2012
Allele-specific expression of APC in adenomatous polyposis families.
Castellsagué E et al.
Gastroenterology, 2010
Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients.
Fostira F et al.
Bmc Cancer, 2010
The genomic landscapes of human breast and colorectal cancers.
Wood LD et al.
Science (new York, N.y.), 2007
Identification and computationally-based structural interpretation of naturally occurring variants of human protein C.
Rovida E et al.
Human Mutation, 2007
The consensus coding sequences of human breast and colorectal cancers.
Sjöblom T et al.
Science (new York, N.y.), 2006