Associated Papers
APC Splicing Mutations Leading to In-Frame Exon 12 or Exon 13 Skipping Are Rare Events in FAP Pathogenesis and Define the Clinical Outcome.
Disciglio V et al.
Genes, 2021
Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners.
Zhang Z et al.
Cell Discovery, 2015
Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signalling.
Brauburger K et al.
The Febs Journal, 2014
Structural basis for the recognition of Asef by adenomatous polyposis coli.
Zhang Z et al.
Cell Research, 2012
Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.
Pfister AS et al.
The Journal of Biological Chemistry, 2012
AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane.
Grohmann A et al.
Journal of Cell Science, 2007
Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Mitin N et al.
Nature Structural & Molecular Biology, 2007
Adenomatous Polyposis Coli (APC) in cell migration.
Fang X et al.
European Journal of Cell Biology, 0
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