Associated Papers
The background puzzle: how identical mutations in the same gene lead to different disease symptoms.
Kammenga JE
The Febs Journal, 2017
Genetic analysis of intestinal polyp development in Collaborative Cross mice carrying the Apc (Min/+) mutation.
Dorman A et al.
Bmc Genetics, 2016
A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts.
Leedham SJ et al.
Gut, 2013
The C-terminus of Apc does not influence intestinal adenoma development or progression.
Lewis A et al.
The Journal of Pathology, 2012
Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.
Lewis A et al.
Gut, 2010
The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression.
Pollard P et al.
Gastroenterology, 2009
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