Associated Papers
Common gene mutations in 103 authenticated colorectal cancer cell lines.
Kranjec C et al.
Oncogenesis, 2026
Decay of driver mutations shapes the landscape of intestinal transformation.
Lourenço FC et al.
Nature, 2026
A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.
Wang P et al.
Genome Biology, 2025
Comprehensive Evaluation of a 1021-Gene Panel in FFPE and Liquid Biopsy for Analytical and Clinical Use.
Meintani A et al.
International Journal of Molecular Sciences, 2025
HDAC and MEK inhibition synergistically suppresses HOXC6 and enhances PD-1 blockade efficacy in BRAFV600E-mutant microsatellite stable colorectal cancer.
Sun Z et al.
Journal for Immunotherapy of Cancer, 2025
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract.
Wu H et al.
Cancer Communications (london, England), 2022
The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway.
Pergolizzi M et al.
Journal of Experimental & Clinical Cancer Research : Cr, 2022
HER2 G776S mutation promotes oncogenic potential in colorectal cancer cells when accompanied by loss of APC function.
Mitani Y et al.
Scientific Reports, 2022
Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy.
Zhang Y et al.
Cell Reports, 2021
A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer.
Xiao J et al.
Bmc Cancer, 2021
Integrated genetic and epigenetic analysis of cancer-related genes in non-ampullary duodenal adenomas and intramucosal adenocarcinomas.
Ota R et al.
The Journal of Pathology, 2020
The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.
Tu J et al.
Scientific Reports, 2019
Serum starvation enhances nonsense mutation readthrough.
Wittenstein A et al.
Journal of Molecular Medicine (berlin, Germany), 2019
The Effects of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer-The Impact in Intratumoral Heterogeneity.
Bettoni F et al.
Frontiers in Oncology, 2019
CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.
Manic G et al.
Gut, 2018
A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients.
Zhang J et al.
Oncotarget, 2017
APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
Tanaka N et al.
Molecular Cancer Therapeutics, 2017
Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling.
Wang W et al.
Neoplasia (new York, N.y.), 2016
The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth.
Nivarthi H et al.
Oncotarget, 2016
Target enrichment using parallel nanoliter quantitative PCR amplification.
De Wilde B et al.
Bmc Genomics, 2014
Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice.
Isoda T et al.
International Journal of Biological Sciences, 2014
CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.
Oberst MD et al.
Mabs, 2014
Pharmaceutical therapies to recode nonsense mutations in inherited diseases.
Lee HL et al.
Pharmacology & Therapeutics, 2012
Combined molecular genetic and cytogenetic analysis from single cells after isothermal whole-genome amplification.
Kroneis T et al.
Clinical Chemistry, 2011
Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cells.
Floquet C et al.
Plos One, 2011
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
Ikediobi ON et al.
Molecular Cancer Therapeutics, 2006
Nuclear accumulation of full-length and truncated adenomatous polyposis coli protein in tumor cells depends on proliferation.
Fagman H et al.
Oncogene, 2003