Associated Papers
Large-scale application of ClinGen-InSiGHT APC-specific ACMG/AMP variant classification criteria leads to substantial reduction in VUS.
Yin X et al.
American Journal of Human Genetics, 2024
Therapy-Associated Polyposis, Late Presentation of a Childhood-Treated Disease.
McGarrity TJ et al.
Acg Case Reports Journal, 2024
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.
Robinson PS et al.
Nature Communications, 2022
Multigene Panel Sequencing Reveals Cancer-Specific and Common Somatic Mutations in Colorectal Cancer Patients: An Egyptian Experience.
Youssef ASE et al.
Current Issues in Molecular Biology, 2022
Prevalence and spectrum of germline cancer susceptibility gene variants and somatic second hits in colorectal cancer.
Liao H et al.
American Journal of Cancer Research, 2021
Exome sequencing and characterization of 49,960 individuals in the UK Biobank.
Van Hout CV et al.
Nature, 2020
Genotyping of Circulating Tumor DNA Reveals the Clinically Actionable Mutation Landscape of Advanced Colorectal Cancer.
Cao W et al.
Molecular Cancer Therapeutics, 2019
Assessment of Tumor Sequencing as a Replacement for Lynch Syndrome Screening and Current Molecular Tests for Patients With Colorectal Cancer.
Hampel H et al.
Jama Oncology, 2018
Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi.
Yeh I et al.
Nature Communications, 2017
T cell neoepitope discovery in colorectal cancer by high throughput profiling of somatic mutations in expressed genes.
Mennonna D et al.
Gut, 2017
Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies.
Kohda M et al.
Familial Cancer, 2016
The importance of G2677T/A and C3435T polymorphisms of the MDR1 gene in the aetiology of colorectal cancer.
Stańko G et al.
Przeglad Gastroenterologiczny, 2016
Colorectal tumors from APC*I1307K carriers principally harbor somatic APC mutations outside the A8 tract.
Zauber P et al.
Plos One, 2014
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas.
Nikolaev SI et al.
Cancer Research, 2012
Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.
Sai K et al.
Expert Opinion on Drug Metabolism & Toxicology, 2011
The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease.
Woods MO et al.
Gut, 2010
Substrate-dependent effects of human ABCB1 coding polymorphisms.
Gow JM et al.
The Journal of Pharmacology and Experimental Therapeutics, 2008
Very high incidence of familial colorectal cancer in Newfoundland: a comparison with Ontario and 13 other population-based studies.
Green RC et al.
Familial Cancer, 2007
Molecular and clinical characteristics in 32 families affected with familial adenomatous polyposis.
Hutter P et al.
Human Mutation, 2001