Varaico: Literature-Extracted Genetic Variants

Gene:APC
Variant:p.S1189*
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APC

NM_000038.6:p.S1189*

Associated Papers

Decay of driver mutations shapes the landscape of intestinal transformation.

Lourenço FC et al.

Nature, 2026

41339549 (PubMed )
Supplement: 41586_2025_9762_MOESM16_ESM.xlsx › ED_Fig_8d

Polyclonality overcomes fitness barriers in Apc-driven tumorigenesis.

Sadien ID et al.

Nature, 2024

39478206 (PubMed )
Supplement: 41586_2024_8053_MOESM5_ESM.xlsx › Fig._2k

Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.

Shah SM et al.

Cancer Research Communications, 2024

38282550 (PubMed )
Supplement: crc-23-0312-s02.xlsx › Fig3A_CRC_data

Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Xie J et al.

Bmc Cancer, 2023

37004022 (PubMed )
Supplement: 12885_2023_10674_MOESM1_ESM.xlsx › data

High Concordance of Genomic Profiles between Primary and Metastatic Colorectal Cancer.

Lee SE et al.

International Journal of Molecular Sciences, 2021

34074070 (PubMed )
Supplement: ijms-22-05561-s001.zip › ijms-1205781-supplementary.xlsx › Table_S1

Next-generation sequencing with comprehensive bioinformatics analysis facilitates somatic mosaic APC gene mutation detection in patients with familial adenomatous polyposis.

Kim B et al.

Bmc Medical Genomics, 2019

May the APC gene somatic mutations in tumor tissues influence the clinical features of Chinese sporadic colorectal cancers?

Liu X et al.

Acta Oncologica (stockholm, Sweden), 2007

[Detection of germline mutations in the APC gene with the protein truncation test].

Liu XR et al.

Yi Chuan Xue Bao = Acta Genetica Sinica, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."