Associated Papers
Common gene mutations in 103 authenticated colorectal cancer cell lines.
Kranjec C et al.
Oncogenesis, 2026
41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10
Nonsense mutation suppression is enhanced by targeting different stages of the protein synthesis process.
Wittenstein A et al.
Plos Biology, 2023
Novel read through agent: ZKN-0013 demonstrates efficacy in APCmin model of familial adenomatous polyposis.
Graf MR et al.
Journal of Molecular Medicine (berlin, Germany), 2023
Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy.
Zhang Y et al.
Cell Reports, 2021
34788622 (PubMed )
Supplement: NIHMS1757901-supplement-2.xlsx › SNVs_indels
Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns.
Mateo L et al.
Genome Medicine, 2020
32907621 (PubMed )
Supplement: 13073_2020_774_MOESM1_ESM.zip › SupplementaryTables › TableS2.xlsx › Driver_Mutations
Serum starvation enhances nonsense mutation readthrough.
Wittenstein A et al.
Journal of Molecular Medicine (berlin, Germany), 2019
Germline POLE mutation in a child with hypermutated medulloblastoma and features of constitutional mismatch repair deficiency.
Lindsay H et al.
Cold Spring Harbor Molecular Case Studies, 2019
A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors.
Menon M et al.
Scientific Reports, 2019
APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
Tanaka N et al.
Molecular Cancer Therapeutics, 2017
BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.
López-García C et al.
Cancer Cell, 2017
28073006 (PubMed )
Supplement: mmc1.pdf
Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing.
Han SW et al.
Plos One, 2013
23700467 (PubMed )
Supplement: pone.0064271.s004.xlsx › Sheet1
Familial adenomatous polyposis: experience from a study of 1164 unrelated german polyposis patients.
Friedl W et al.
Hereditary Cancer in Clinical Practice, 2005
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.
Lamlum H et al.
Nature Medicine, 1999
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