Varaico: Literature-Extracted Genetic Variants

Gene:APC
Variant:p.F1378delFs
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APC

NM_001127511.3:p.F1378delFs

Associated Papers

Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy.

Yamamoto T et al.

Cancers, 2020

32708005 (PubMed )
Supplement: cancers-12-02010-s001.pdf

Inactivation of promoter 1B of APC causes partial gene silencing: evidence for a significant role of the promoter in regulation and causative of familial adenomatous polyposis.

Rohlin A et al.

Oncogene, 2011

Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.

Crabtree M et al.

Oncogene, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."