Associated Papers
Glutathionylated DNA adducts accumulate in mitochondrial DNA and are regulated by AP endonuclease 1 and tyrosyl-DNA phosphodiesterase 1.
Chen YH et al.
Proceedings of the National Academy of Sciences of the United States of America, 2025
The DNA-repair protein APE1 participates with hnRNPA2B1 to motif-enriched and prognostic miRNA secretion.
Mangiapane G et al.
Oncogene, 2024
DNA Repair Protein APE1 Degrades Dysfunctional Abasic mRNA in Mitochondria Affecting Oxidative Phosphorylation.
Barchiesi A et al.
Journal of Molecular Biology, 2021
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.
Antoniali G et al.
Nature Communications, 2017
Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastoma.
Ströbel T et al.
Scientific Reports, 2017
Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3'-diesterase-deficient strain.
Wang Z et al.
Dna Repair, 2014
Human apurinic/apyrimidinic endonuclease 1.
Li M et al.
Antioxidants & Redox Signaling, 2014
Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function.
Vascotto C et al.
Molecular Biology of the Cell, 2011
Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.
Mantha AK et al.
Journal of Molecular Biology, 2008
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