Varaico: Literature-Extracted Genetic Variants

Gene:APEX1
Variant:p.D70A
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APEX1

NM_001641.4:p.D70A

Associated Papers

Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.

McNeill DR et al.

Mutagenesis, 2020

Human apurinic/apyrimidinic endonuclease 1 (APE1) has 3' RNA phosphatase and 3' exoribonuclease activities.

Chohan M et al.

Journal of Molecular Biology, 2015

Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family.

Castillo-Acosta VM et al.

Nucleic Acids Research, 2009

Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function.

Xi T et al.

Genomics, 2004

Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.

Shen MR et al.

Cancer Research, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."