Associated Papers
Targeting APE1 endonuclease activity impairs metastasis and enhances genotoxic therapy response in pancreatic cancer.
Kpenu EK et al.
Research Square, 2025
The DNA-repair protein APE1 participates with hnRNPA2B1 to motif-enriched and prognostic miRNA secretion.
Mangiapane G et al.
Oncogene, 2024
Structural basis for APE1 processing DNA damage in the nucleosome.
Weaver TM et al.
Nature Communications, 2022
DNA Repair Protein APE1 Degrades Dysfunctional Abasic mRNA in Mitochondria Affecting Oxidative Phosphorylation.
Barchiesi A et al.
Journal of Molecular Biology, 2021
DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity.
Li J et al.
Oncotarget, 2018
Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2.
Malfatti MC et al.
Nucleic Acids Research, 2017
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.
Antoniali G et al.
Nature Communications, 2017
SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements.
Antoniali G et al.
Molecular Biology of the Cell, 2014
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.
Tsutakawa SE et al.
The Journal of Biological Chemistry, 2013
Lys98 substitution in human AP endonuclease 1 affects the kinetic mechanism of enzyme action in base excision and nucleotide incision repair pathways.
Timofeyeva NA et al.
Plos One, 2011
MD simulation and experimental evidence for Mg²+ binding at the B site in human AP endonuclease 1.
Oezguen N et al.
Bioinformation, 2011
Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity.
Gelin A et al.
Plos One, 2010
Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease.
Izumi T et al.
Journal of Molecular Biology, 1999
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