Varaico: Literature-Extracted Genetic Variants

Gene:APEX1
Variant:p.K98R
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APEX1

NM_001641.4:p.K98R

Associated Papers

Lys98 substitution in human AP endonuclease 1 affects the kinetic mechanism of enzyme action in base excision and nucleotide incision repair pathways.

Timofeyeva NA et al.

Plos One, 2011

Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity.

Gelin A et al.

Plos One, 2010

Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.

Mantha AK et al.

Journal of Molecular Biology, 2008

Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease.

Izumi T et al.

Journal of Molecular Biology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."