Varaico: Literature-Extracted Genetic Variants

Gene:APEX1
Variant:p.D148E
Back to variants list

APEX1

NM_001641.4:p.D148E

Associated Papers

Impact of pesticide exposure on base excision repair gene polymorphisms in the Haryana population.

Gulia H et al.

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 2025

Molecular Mechanisms of Preventable Causes of Oral Cancer and Precancer Through Polymorphism in DNA Base Excision Repair Genes in Patients with Tobacco Products Habits.

Sundaram E et al.

Journal of Maxillofacial and Oral Surgery, 2025

Genetic Polymorphism of MDM2 Gene Associates with Breast Cancer Incidence in the Lower Northern Thailand.

Srikummool M et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2025

XRCC1 Arg399Gln Genetic Variant Increases Colorectal Cancer Susceptibility: A Comprehensive Meta-Analysis.

Kampalli PK et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2025

41312940 (PubMed )
Supplement: APJCP-26-11-4127-s001.pdf

Oxidative DNA damage and DNA repair gene variants in differentiated thyroid cancer patients treated with radioactive iodine.

Avsar FN et al.

Endocrine, 2025

Molecular Duality of OGG1: From Genomic Guardian to Redox-Sensitive Modulator in Diseases.

Zhong R et al.

Antioxidants (basel, Switzerland), 2025

The Link Between Human Alkyladenine DNA Glycosylase and Cancer Development.

Kladova OA et al.

International Journal of Molecular Sciences, 2025

A Case-Control Study on Combined Effects of Base Excision Repair and Nucleotide Excision Repair Gene Polymorphisms in Gastrointestinal Cancer Susceptibility.

Datkhile KD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2025

Integrative Computational Analysis of Common EXO5 Haplotypes: Impact on Protein Dynamics, Genome Stability, and Cancer Progression.

Mazza F et al.

Journal of Chemical Information and Modeling, 2025

40115981 (PubMed )
Supplement: ci5c00067_si_002.xlsx › scored_ALL_haplotypes_1MAF_cano

APEX1 Polymorphisms Affect Acute Myeloid Leukemia Risk, and Its Expression Is Involved in Cell Proliferation and Differentiation.

Gotoh N et al.

International Journal of Laboratory Hematology, 2025

Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.

Kuras M et al.

Cancers, 2025

40075679 (PubMed )
Supplement: cancers-17-00832-s001.zip › Table_S5._SAAVs.xlsx › Table_S5A

A rare genetic variant in APEX1 is associated with familial amyotrophic lateral sclerosis with slow progression.

Mi Y et al.

Acta Neurologica Belgica, 2025

Genomic instability in ovarian cancer: Through the lens of single nucleotide polymorphisms.

Canchi Sistla H et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2025

Unveiling the molecular profile of a prostate carcinoma: implications for personalized medicine.

Agostini M et al.

Biology Direct, 2024

Genetic Polymorphisms of DNA Repair Genes and their Influence on Paclitaxel based Chemotherapy Induced Toxicity Reactions in Breast Cancer Patients.

Datkhile KD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2024

AR (CAG)n Microsatellite and APEX1 c.444T>G (p.Asp148Glu) Polymorphisms as Independent Prognostic Biomarkers in Prostate Cancer: Insights from an Argentinian Cohort.

Pascual G et al.

Cancers, 2024

Single Nucleotide Polymorphisms in APE1, hOGG1, RAD51 Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients.

Gudur AK et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2024

Investigating Tobacco's Impact on DNA Repair Genes and Risks in Oral Precancer and Cancer: A Comprehensive Research Study.

Mohammad S et al.

Journal of Maxillofacial and Oral Surgery, 2024

Genetic variations in DNA excision repair pathway contribute to the chemosensitivity and prognosis of acute myeloid leukemia.

Zhang A et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2024

Genetic Associations of Primary Angle-Closure Disease: A Systematic Review and Meta-Analysis.

Liang YJ et al.

Jama Ophthalmology, 2024

A Primary Telangiectatic Mandibular Osteosarcoma With Germ-Line Malignancy-Associated DNA Damage Repair Gene Polymorphisms: A Case Report.

Tahir M et al.

Case Reports in Oncological Medicine, 2024

Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review.

Zheng Y et al.

Frontiers in Pharmacology, 2024

Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.

Huang YC et al.

Journal of Personalized Medicine, 2023

37763159 (PubMed )
Supplement: jpm-13-01392-s001.zip › Supplementary_Table_S3.xlsx › Variants

Understanding DNA Damage Response and DNA Repair in Multiple Myeloma.

Petrilla C et al.

Cancers, 2023

Nuclear genetic control of mtDNA copy number and heteroplasmy in humans.

Gupta R et al.

Nature, 2023

Single-Nucleotide Polymorphisms in Base-Excision Repair-Related Genes Involved in the Risk of an Occurrence of Non-Alcoholic Fatty Liver Disease.

Ziółkowska S et al.

International Journal of Molecular Sciences, 2023

Lung cancer risk in workers occupationally exposed to polycyclic aromatic hydrocarbons with emphasis on the role of DNA repair gene.

Moubarz G et al.

International Archives of Occupational and Environmental Health, 2023

Genetic contribution between APE1 variants in polycystic ovarian syndrome.

Al-Mutawa J

Saudi Journal of Biological Sciences, 2023

Neural Tube Defects and Folate Deficiency: Is DNA Repair Defective?

Wang X et al.

International Journal of Molecular Sciences, 2023

The interplay between XPG-Asp1104His polymorphism and reproductive risk factors elevates risk of breast cancer in Tanzanian women: A multiple interaction analysis.

Adolf IC et al.

Cancer Medicine, 2023

Decoding the genetic relationship between Alzheimer's disease and type 2 diabetes: potential risk variants and future direction for North Africa.

Boukhalfa W et al.

Frontiers in Aging Neuroscience, 2023

37342358 (PubMed )
Supplement: Table_2.XLSX › Table_2_SNPnexus_annotation

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Valentine H et al.

Cancer Research Communications, 2022

36643868 (PubMed )
Supplement: crc-22-0245-s07.xlsx › Variants_All_Exonic.exclude_ncR

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM2_ESM.xlsx › Literature_review_table

Impact of germline polymorphisms in genes regulating glucose uptake on positron emission tomography findings and outcome in diffuse large B-cell lymphoma: results from the PETAL trial.

Broecker-Preuss M et al.

Journal of Cancer Research and Clinical Oncology, 2022

Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.

Cukier HN et al.

Npj Parkinson's Disease, 2022

35768426 (PubMed )
Supplement: 41531_2022_346_MOESM2_ESM.xlsx › SupTab1

Impact of Polymorphism in Base Excision Repair and Nucleotide Excision Repair Genes and Risk of Cervical Cancer: A Case-Control Study.

Datkhile KD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2022

Polymorphisms in DNA Repair and Xenobiotic Biotransformation Enzyme Genes and Lung Cancer Risk in Coal Mine Workers.

Minina V et al.

Life (basel, Switzerland), 2022

Association study of candidate DNA-repair gene variants and acute graft versus host disease in pediatric patients receiving allogeneic hematopoietic stem-cell transplantation.

Uppugunduri CRS et al.

The Pharmacogenomics Journal, 2022

Association of genetic polymorphisms in DNA repair genes ERCC2 Asp312Asn (rs1799793), ERCC2 Lys 751 Gln (rs13181), XRCC1 Arg399 Gln (rs25487) and XRCC3 Thr 241Met (rs861539) with the susceptibility of lung cancer in Saudi population.

Alsagaby S et al.

Nucleosides, Nucleotides & Nucleic Acids, 2022

Association of APEX1 and XRCC1 Gene Polymorphisms With HIV-1 Infection Susceptibility and AIDS Progression in a Northern Chinese MSM Population.

Liu B et al.

Frontiers in Genetics, 2022

Targeting DNA damage response as a potential therapeutic strategy for head and neck squamous cell carcinoma.

Lei H et al.

Frontiers in Oncology, 2022

Genetic variants of APEX1 p.Asp148Glu and XRCC1 p.Gln399Arg with the susceptibility of hepatocellular carcinoma.

Saad AM et al.

Journal of Medical Virology, 2021

Genetic polymorphisms in DNA repair genes and hepatocellular carcinoma risk.

Ghaderi-Zefrehi H et al.

Dna Repair, 2021

Genetic Polymorphisms in DNA Repair Gene APE1/Ref-1 and the Risk of Neural Tube Defects in a High-Risk Area of China.

Wang X et al.

Reproductive Sciences (thousand Oaks, Calif.), 2021

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM11_ESM.xlsx › Supplementary_Data_8

Mitochondrial genome stability in human: understanding the role of DNA repair pathways.

Dahal S et al.

The Biochemical Journal, 2021

ASSOCIATION BETWEEN APE1 GENE AND LUNG CANCER IN IRAQI POPULATION.

Ahmed MM

Wiadomosci Lekarskie (warsaw, Poland : 1960), 2021

Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Zhang J et al.

Frontiers in Oncology, 2021

35087742 (PubMed )
Supplement: Table_1.xlsx › Table3_mut_frequency_v3

Association between APE1 ASP148GLU and colorectal cancer risk: A meta-analysis.

Lin C et al.

Clinical and Investigative Medicine. Medecine Clinique Et Experimentale, 2020

1–50 of 398 papers
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."