Varaico: Literature-Extracted Genetic Variants

Gene:APEX1
Variant:p.D210H
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APEX1

NM_001641.4:p.D210H

Associated Papers

Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.

Tsutakawa SE et al.

The Journal of Biological Chemistry, 2013

Pre-steady-state kinetic characterization of the AP endonuclease activity of human AP endonuclease 1.

Maher RL et al.

The Journal of Biological Chemistry, 2007

Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function.

Xi T et al.

Genomics, 2004

Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.

Shen MR et al.

Cancer Research, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."