Associated Papers
Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins.
Kladova OA et al.
International Journal of Molecular Sciences, 2020
Chromatin and other obstacles to base excision repair: potential roles in carcinogenesis.
Caffrey PJ et al.
Mutagenesis, 2020
Emerging Evidence Highlighting the Importance of Redox Dysregulation in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS).
Jagaraj CJ et al.
Frontiers in Cellular Neuroscience, 2020
The impact of single-nucleotide polymorphisms of human apurinic/apyrimidinic endonuclease 1 on specific DNA binding and catalysis.
Alekseeva IV et al.
Biochimie, 2019
Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.
Leong TL et al.
Oncogene, 2019
Validation and Clinical Applications of a Comprehensive Next Generation Sequencing System for Molecular Characterization of Solid Cancer Tissues.
Dehghani M et al.
Frontiers in Molecular Biosciences, 2019
DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity.
Li J et al.
Oncotarget, 2018
Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.
Pritchard AL et al.
Plos One, 2018
Tumor-associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes.
Illuzzi JL et al.
Environmental and Molecular Mutagenesis, 2017
Reduced Nuclease Activity of Apurinic/Apyrimidinic Endonuclease (APE1) Variants on Nucleosomes: IDENTIFICATION OF ACCESS RESIDUES.
Hinz JM et al.
The Journal of Biological Chemistry, 2015
Human apurinic/apyrimidinic endonuclease 1 (APE1) has 3' RNA phosphatase and 3' exoribonuclease activities.
Chohan M et al.
Journal of Molecular Biology, 2015
Human apurinic/apyrimidinic endonuclease 1.
Li M et al.
Antioxidants & Redox Signaling, 2014
Altered endoribonuclease activity of apurinic/apyrimidinic endonuclease 1 variants identified in the human population.
Kim WC et al.
Plos One, 2014
Functional assessment of population and tumor-associated APE1 protein variants.
Illuzzi JL et al.
Plos One, 2013
Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry.
Kirkali G et al.
Plos One, 2013
Reprint of: gene susceptibility to oxidative damage: from single nucleotide polymorphisms to function.
Simonelli V et al.
Mutation Research, 2012
Gene susceptibility to oxidative damage: from single nucleotide polymorphisms to function.
Simonelli V et al.
Mutation Research, 2012
Investigating the structural impacts of I64T and P311S mutations in APE1-DNA complex: a molecular dynamics approach.
Doss CG et al.
Plos One, 2012
Variation in base excision repair capacity.
Wilson DM et al.
Mutation Research, 2011
Micronucleus occurrence related to base excision repair gene polymorphisms in Chinese workers occupationally exposed to vinyl chloride monomer.
Wen-Bin M et al.
Journal of Occupational and Environmental Medicine, 2009
Cancer pharmacogenomics: role of DNA repair genetic polymorphisms in individualizing cancer therapy.
Gossage L et al.
Molecular Diagnosis & Therapy, 2007
Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.
Zienolddiny S et al.
Carcinogenesis, 2006
Gene-environment interactions between the smoking habit and polymorphisms in the DNA repair genes, APE1 Asp148Glu and XRCC1 Arg399Gln, in Japanese lung cancer risk.
Ito H et al.
Carcinogenesis, 2004
Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function.
Xi T et al.
Genomics, 2004
Functional characterization of Ape1 variants identified in the human population.
Hadi MZ et al.
Nucleic Acids Research, 2000
Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.
Shen MR et al.
Cancer Research, 1998