Varaico: Literature-Extracted Genetic Variants

Gene:APEX1
Variant:p.D283G
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APEX1

NM_001641.4:p.D283G

Associated Papers

Mitochondrial genome stability in human: understanding the role of DNA repair pathways.

Dahal S et al.

The Biochemical Journal, 2021

Sorafenib Resistance in Hepatocellular Carcinoma: The Relevance of Genetic Heterogeneity.

Cabral LKD et al.

Cancers, 2020

APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation.

Lirussi L et al.

Oncotarget, 2016

Human apurinic/apyrimidinic endonuclease 1.

Li M et al.

Antioxidants & Redox Signaling, 2014

Functional assessment of population and tumor-associated APE1 protein variants.

Illuzzi JL et al.

Plos One, 2013

Base excision repair and cancer.

Wallace SS et al.

Cancer Letters, 2012

Cancer pharmacogenomics: role of DNA repair genetic polymorphisms in individualizing cancer therapy.

Gossage L et al.

Molecular Diagnosis & Therapy, 2007

Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function.

Xi T et al.

Genomics, 2004

Functional characterization of Ape1 variants identified in the human population.

Hadi MZ et al.

Nucleic Acids Research, 2000

Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.

Shen MR et al.

Cancer Research, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."