Varaico: Literature-Extracted Genetic Variants

Gene:APEX1
Variant:p.H309N
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APEX1

NM_001641.4:p.H309N

Associated Papers

Human apurinic/apyrimidinic endonuclease 1 (APE1) has 3' RNA phosphatase and 3' exoribonuclease activities.

Chohan M et al.

Journal of Molecular Biology, 2015

Human apurinic/apyrimidinic endonuclease 1.

Li M et al.

Antioxidants & Redox Signaling, 2014

Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.

Tsutakawa SE et al.

The Journal of Biological Chemistry, 2013

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function.

Vascotto C et al.

Molecular Biology of the Cell, 2011

MD simulation and experimental evidence for Mg²+ binding at the B site in human AP endonuclease 1.

Oezguen N et al.

Bioinformation, 2011

Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.

Mantha AK et al.

Journal of Molecular Biology, 2008

Pre-steady-state kinetic characterization of the AP endonuclease activity of human AP endonuclease 1.

Maher RL et al.

The Journal of Biological Chemistry, 2007

Regulation of WRN helicase activity in human base excision repair.

Ahn B et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."