Varaico: Literature-Extracted Genetic Variants

Gene:APEX1
Variant:p.C310S
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APEX1

NM_001641.4:p.C310S

Associated Papers

Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3'-diesterase-deficient strain.

Wang Z et al.

Dna Repair, 2014

A zinc linchpin motif in the MUTYH glycosylase interdomain connector is required for efficient repair of DNA damage.

Engstrom LM et al.

Journal of the American Chemical Society, 2014

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function.

Vascotto C et al.

Molecular Biology of the Cell, 2011

Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.

Mantha AK et al.

Journal of Molecular Biology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."