Associated Papers
In Silico Tools and Approaches for the Prediction of Functional and Structural Effects of Single-Nucleotide Polymorphisms on Proteins: An Expert Review.
Yazar M et al.
Omics : a Journal of Integrative Biology, 2021
Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins.
Kladova OA et al.
International Journal of Molecular Sciences, 2020
The impact of single-nucleotide polymorphisms of human apurinic/apyrimidinic endonuclease 1 on specific DNA binding and catalysis.
Alekseeva IV et al.
Biochimie, 2019
DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity.
Li J et al.
Oncotarget, 2018
30167090 (PubMed )
Supplement: oncotarget-09-31719-s001.pdf
Tumor-associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes.
Illuzzi JL et al.
Environmental and Molecular Mutagenesis, 2017
Structural characterization of single nucleotide variants at ligand binding sites and enzyme active sites of human proteins.
Yamada KD et al.
Biophysics and Physicobiology, 2016
Reduced Nuclease Activity of Apurinic/Apyrimidinic Endonuclease (APE1) Variants on Nucleosomes: IDENTIFICATION OF ACCESS RESIDUES.
Hinz JM et al.
The Journal of Biological Chemistry, 2015
Human apurinic/apyrimidinic endonuclease 1 (APE1) has 3' RNA phosphatase and 3' exoribonuclease activities.
Chohan M et al.
Journal of Molecular Biology, 2015
Human apurinic/apyrimidinic endonuclease 1.
Li M et al.
Antioxidants & Redox Signaling, 2014
Structure-function studies on non-synonymous SNPs of chemokine receptor gene implicated in cardiovascular disease: a computational approach.
Sai Ramesh A et al.
The Protein Journal, 2013
Functional assessment of population and tumor-associated APE1 protein variants.
Illuzzi JL et al.
Plos One, 2013
Investigating the structural impacts of I64T and P311S mutations in APE1-DNA complex: a molecular dynamics approach.
Doss CG et al.
Plos One, 2012
Bioinformatic processing to identify single nucleotide polymorphism that potentially affect Ape1 function.
Yu ET et al.
Mutation Research, 2011
Variation in base excision repair capacity.
Wilson DM et al.
Mutation Research, 2011
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