Associated Papers
Characterization of APH-1 mutants with a disrupted transmembrane GxxxG motif.
Araki W et al.
Journal of Molecular Neuroscience : Mn, 2006
Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving intermolecular and intramolecular interactions.
Niimura M et al.
The Journal of Biological Chemistry, 2005
Co-expression of nicastrin and presenilin rescues a loss of function mutant of APH-1.
Edbauer D et al.
The Journal of Biological Chemistry, 2004
A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex.
Lee SF et al.
The Journal of Biological Chemistry, 2004
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