Varaico: Literature-Extracted Genetic Variants

Gene:APOBEC3A
Variant:p.C106S
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APOBEC3A

NM_145699.4:p.C106S

Associated Papers

BRCA2 deficiency and replication stress drive APOBEC3-Mediated genomic instability.

Situ K et al.

Nature Communications, 2025

Defining the genome-wide mutagenic impact of APOBEC3 enzymes.

Németh E et al.

Methods in Enzymology, 2025

The cytidine deaminase APOBEC3A regulates nucleolar function to promote cell growth and ribosome biogenesis.

McCool MA et al.

Plos Biology, 2024

APOBEC3A regulates transcription from interferon-stimulated response elements.

Taura M et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity.

Green AM et al.

Embo Reports, 2021

Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response.

Wang X et al.

Cell Reports, 2020

Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.

Green AM et al.

Cancer Research, 2017

Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity.

Horn AV et al.

Nucleic Acids Research, 2014

Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.

Mitra M et al.

Nucleic Acids Research, 2014

Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase.

Narvaiza I et al.

Plos Pathogens, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."