Associated Papers
Analysis of Cytosine Base Editors in Bovine Zygotes: Efficiency and Editing Window Characterization Through Targeting the MYO7A Gene.
Ryu J et al.
Current Issues in Molecular Biology, 2025
Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering.
Cheng P et al.
Cell Research, 2024
nCas9 Engineering for Improved Target Interaction Presents an Effective Strategy to Enhance Base Editing.
Zhang G et al.
Advanced Science (weinheim, Baden-wurttemberg, Germany), 2024
Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor.
Wei Y et al.
Protein & Cell, 2023
TadA reprogramming to generate potent miniature base editors with high precision.
Zhang S et al.
Nature Communications, 2023
Efficient Simultaneous Introduction of Premature Stop Codons in Three Tumor Suppressor Genes in PFFs via a Cytosine Base Editor.
Jiang H et al.
Genes, 2022
CABE-RY: A PAM-flexible dual-mutation base editor for reliable modeling of multi-nucleotide variants.
Tao W et al.
Molecular Therapy. Nucleic Acids, 2021
34513298 (PubMed )
Supplement: mmc1.pdf
Creating RNA Specific C-to-U Editase from APOBEC3A by Separation of Its Activities on DNA and RNA Substrates.
Tang G et al.
Acs Synthetic Biology, 2021
Base editing: advances and therapeutic opportunities.
Porto EM et al.
Nature Reviews. Drug Discovery, 2020
Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response.
Wang X et al.
Cell Reports, 2020
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities.
Gehrke JM et al.
Nature Biotechnology, 2018
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
Mitra M et al.
Nucleic Acids Research, 2014
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