Associated Papers
APOBEC3A drives deaminase mutagenesis in human gastric epithelium.
An Y et al.
Genome Research, 2025
Tobacco smoke carcinogens exacerbate APOBEC mutagenesis and carcinogenesis.
Durfee C et al.
Research Square, 2025
Tobacco smoke carcinogens exacerbate APOBEC mutagenesis and carcinogenesis.
Durfee C et al.
Biorxiv : the Preprint Server for Biology, 2025
APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats.
Brown RE et al.
Proceedings of the National Academy of Sciences of the United States of America, 2025
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
Caswell DR et al.
Nature Genetics, 2024
Acute expression of human APOBEC3B in mice results in RNA editing and lethality.
Alonso de la Vega A et al.
Genome Biology, 2023
Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer.
Carpenter MA et al.
Plos Genetics, 2023
Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases.
Durfee C et al.
Cell Reports. Medicine, 2023
Identification of natural product 3, 5-diiodotyrosine as APOBEC3B inhibitor to prevent somatic mutation accumulation and cancer progression.
Chen C et al.
Journal for Immunotherapy of Cancer, 2022
Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features.
Buisson R et al.
Science (new York, N.y.), 2019
Structural Analysis of the Active Site and DNA Binding of Human Cytidine Deaminase APOBEC3B.
Hou S et al.
Journal of Chemical Theory and Computation, 2019
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.
Shi K et al.
Scientific Reports, 2017
Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.
Xiao X et al.
Nucleic Acids Research, 2017
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
Shi K et al.
The Journal of Biological Chemistry, 2015
Characterization of the Catalytic Domain of Human APOBEC3B and the Critical Structural Role for a Conserved Methionine.
Siriwardena SU et al.
Journal of Molecular Biology, 2015
Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma.
Zhang T et al.
Human Molecular Genetics, 2013