Varaico: Literature-Extracted Genetic Variants

Gene:APOBEC3G
Variant:p.H257R
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APOBEC3G

NM_021822.4:p.H257R

Associated Papers

Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity.

Horn AV et al.

Nucleic Acids Research, 2014

The innate antiviral factor APOBEC3G targets replication of measles, mumps and respiratory syncytial viruses.

Fehrholz M et al.

The Journal of General Virology, 2012

Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA.

Friew YN et al.

Retrovirology, 2009

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G.

Holmes RK et al.

The Journal of Biological Chemistry, 2007

The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.

Shindo K et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."