Associated Papers
Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity.
Schwartz I et al.
Nature Communications, 2026
Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer.
Carpenter MA et al.
Plos Genetics, 2023
Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome.
Nakata Y et al.
Nucleic Acids Research, 2023
36610792 (PubMed )
Supplement: gkac1238_supplemental_file.pdf
Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity.
Chesarino NM et al.
Viruses, 2020
The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H.
Wang J et al.
Journal of Molecular Biology, 2019
Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features.
Buisson R et al.
Science (new York, N.y.), 2019
Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA.
Matsuoka T et al.
Nucleic Acids Research, 2018
The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
Shaban NM et al.
Molecular Cell, 2018
Stably expressed APOBEC3H forms a barrier for cross-species transmission of simian immunodeficiency virus of chimpanzee to humans.
Zhang Z et al.
Plos Pathogens, 2017
APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA.
Bohn JA et al.
Nature Communications, 2017
Biochemical Characterization of APOBEC3H Variants: Implications for Their HIV-1 Restriction Activity and mC Modification.
Gu J et al.
Journal of Molecular Biology, 2016
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.
Starrett GJ et al.
Nature Communications, 2016
Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities.
Mitra M et al.
Retrovirology, 2015
The localization of APOBEC3H variants in HIV-1 virions determines their antiviral activity.
Ooms M et al.
Journal of Virology, 2010
Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H.
Harari A et al.
Journal of Virology, 2009
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