Varaico: Literature-Extracted Genetic Variants

Gene:APOBEC3H
Variant:p.G105R
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APOBEC3H

NM_181773.5:p.G105R

Associated Papers

Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity.

Schwartz I et al.

Nature Communications, 2026

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Valentine H et al.

Cancer Research Communications, 2022

36643868 (PubMed )
Supplement: crc-22-0245-s07.xlsx › Variants_All_Exonic.exclude_ncR

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry.

Bateman NW et al.

Iscience, 2022

35036865 (PubMed )
Supplement: mmc2.xlsx › SupplementalTable1A

APOBEC3-induced mutation of the hepatitis virus B DNA genome occurs during its viral RNA reverse transcription into (-)-DNA.

Chen Z et al.

The Journal of Biological Chemistry, 2021

Human APOBEC3 Variations and Viral Infection.

Sadeghpour S et al.

Viruses, 2021

Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms.

McDonnell MM et al.

Plos Pathogens, 2021

Single-nucleotide polymorphism of the DNA cytosine deaminase APOBEC3H haplotype I leads to enzyme destabilization and correlates with lung cancer.

Hix MA et al.

Nar Cancer, 2020

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.

Calender A et al.

Bmc Medical Genomics, 2018

29510755 (PubMed )
Supplement: 12920_2018_338_MOESM6_ESM.xlsx › Feuil3

Biochemical Characterization of APOBEC3H Variants: Implications for Their HIV-1 Restriction Activity and mC Modification.

Gu J et al.

Journal of Molecular Biology, 2016

APOBEC3H polymorphisms and susceptibility to HIV-1 infection in an Indian population.

Naruse TK et al.

Journal of Human Genetics, 2016

Natural Polymorphisms and Oligomerization of Human APOBEC3H Contribute to Single-stranded DNA Scanning Ability.

Feng Y et al.

The Journal of Biological Chemistry, 2015

APOBEC3H polymorphisms associated with the susceptibility to HIV-1 infection and AIDS progression in Japanese.

Sakurai D et al.

Immunogenetics, 2015

Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection.

Kim EY et al.

Plos Pathogens, 2014

Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements.

Egan JB et al.

Plos One, 2014

24505276 (PubMed )
Supplement: pone.0087113.s004.xls › Table_S3

Genetic variants in the host restriction factor APOBEC3G are associated with HIV-1-related disease progression and central nervous system impairment in children.

Singh KK et al.

Journal of Acquired Immune Deficiency Syndromes (1999), 2013

APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages.

Chaipan C et al.

Journal of Virology, 2013

Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities.

Zhen A et al.

Plos One, 2012

A positively selected APOBEC3H haplotype is associated with natural resistance to HIV-1 infection.

Cagliani R et al.

Evolution; International Journal of Organic Evolution, 2011

Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity.

Li MM et al.

Journal of Virology, 2011

Analysis of human APOBEC3H haplotypes and anti-human immunodeficiency virus type 1 activity.

Wang X et al.

Journal of Virology, 2011

The localization of APOBEC3H variants in HIV-1 virions determines their antiviral activity.

Ooms M et al.

Journal of Virology, 2010

The range of human APOBEC3H sensitivity to lentiviral Vif proteins.

Li MM et al.

Journal of Virology, 2010

Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1.

Tan L et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2009

Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H.

Harari A et al.

Journal of Virology, 2009

Antiretroelement activity of APOBEC3H was lost twice in recent human evolution.

OhAinle M et al.

Cell Host & Microbe, 2008

Predicting nsSNPs that Disrupt Protein-Protein Interactions Using Docking.

Goodacre N et al.

Ieee/acm Transactions on Computational Biology and Bioinformatics, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."