Associated Papers
Apolipoprotein C-III amyloidosis in white lions (Panthera leo).
Kobayashi N et al.
Veterinary Pathology, 2024
APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups.
Goyal S et al.
Lipids in Health and Disease, 2021
Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation.
Hsueh WC et al.
Circulation. Cardiovascular Genetics, 2017
The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation.
Sundaram M et al.
Journal of Lipid Research, 2017
A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
Khetarpal SA et al.
Nature Medicine, 2017
Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.
Drenos F et al.
Circulation. Cardiovascular Genetics, 2016
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
Crosby J et al.
The New England Journal of Medicine, 2014
Clinical proteome informatics workbench detects pathogenic mutations in hereditary amyloidoses.
Dasari S et al.
Journal of Proteome Research, 2014
Two novel mutations in apolipoprotein C3 underlie atheroprotective lipid profiles in families.
Bochem AE et al.
Clinical Genetics, 2014
Human apolipoprotein C-III - a new intrahepatic protein factor promoting assembly and secretion of very low density lipoproteins.
Yao Z
Cardiovascular & Hematological Disorders Drug Targets, 2012
Intrahepatic role of exchangeable apolipoproteins in lipoprotein assembly and secretion.
Sundaram M et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2012
Missense mutation in APOC3 within the C-terminal lipid binding domain of human ApoC-III results in impaired assembly and secretion of triacylglycerol-rich very low density lipoproteins: evidence that ApoC-III plays a major role in the formation of lipid precursors within the microsomal lumen.
Qin W et al.
The Journal of Biological Chemistry, 2011
Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia.
Sundaram M et al.
Journal of Lipid Research, 2010
Genetic determinants of plasma triglycerides: impact of rare and common mutations.
Talmud PJ
Current Atherosclerosis Reports, 2001
Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr.
Liu H et al.
Journal of Lipid Research, 2000