Varaico: Literature-Extracted Genetic Variants

Gene:APOC3
Variant:p.R60Splc
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APOC3

NM_000040.3:p.R60Splc

Associated Papers

Understanding Hypertriglyceridemia: Integrating Genetic Insights.

Alves M et al.

Genes, 2024

Genetics and regulation of HDL metabolism.

Kardassis D et al.

Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids, 2022

Ethnic differences in ApoC-III concentration and the risk of cardiovascular disease: No evidence for the cardioprotective role of rare/loss of function APOC3 variants in non-Europeans.

Rout M et al.

American Heart Journal Plus : Cardiology Research and Practice, 2022

APOC3 rs2070667 Associates with Serum Triglyceride Profile and Hepatic Inflammation in Nonalcoholic Fatty Liver Disease.

Xu QY et al.

Biomed Research International, 2020

Emerging evidences for the opposite role of apolipoprotein C3 and apolipoprotein A5 in lipid metabolism and coronary artery disease.

Dai W et al.

Lipids in Health and Disease, 2019

Emerging Evidence that ApoC-III Inhibitors Provide Novel Options to Reduce the Residual CVD.

Taskinen MR et al.

Current Atherosclerosis Reports, 2019

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.

Khetarpal SA et al.

Nature Medicine, 2017

What can we learn about lipoprotein metabolism and coronary heart disease from studying rare variants?

Jeff JM et al.

Current Opinion in Lipidology, 2016

Association of APOC3 Loss-of-Function Mutations With Plasma Lipids and Subclinical Atherosclerosis: The Multi-Ethnic BioImage Study.

Natarajan P et al.

Journal of the American College of Cardiology, 2015

Genetics. APOC3 mutations lower CVD risk.

Geach T

Nature Reviews. Cardiology, 2014

Loss-of-function mutations in APOC3, triglycerides, and coronary disease.

Crosby J et al.

The New England Journal of Medicine, 2014

APOC3 may not be a predictor of risk of ischemic vascular disease in the Chinese population.

Tang L et al.

F1000research, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."